Indication and Usage
CANASA® (mesalamine) 1000 mg rectal suppositories is a prescription medicine used to treat active ulcerative proctitis. It is not known if CANASA is safe and effective for use for longer than 6 weeks.

Important Safety Information
You should not use CANASA if you are allergic to medicines that contain salicylates, including aspirin, or are allergic to mesalamine or any of the ingredients in CANASA.

Before using CANASA, tell your doctor if you have a history of allergic reactions to the medicine sulfasalazine, have or have had kidney problems, pericarditis (inflamed sac around your heart), have any other medical condition, if you are pregnant or plan to become pregnant, or if you are breastfeeding or plan to breastfeed. You and your doctor will decide if you should use CANASA.

The most common side effects of CANASA include dizziness, acne, colitis (inflammation of the colon), rectal pain (pain in the final portion of the large intestine), fever, and rash.

Less common, but possibly serious side effects include a reaction to the medicine (acute intolerance syndrome) that includes cramps, sharp abdominal (stomach area) pain, bloody diarrhea, and sometimes fever, headache, and rash. In rare cases, the sac around the heart may become inflamed (pericarditis). Chest pain or shortness of breath is a sign of this problem. Stop use and tell your doctor right away if you get any of these symptoms. Other side effects not listed above may also occur in some patients.

Call your doctor for medical advice about side effects. You may report side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.


Please see the link for full US Prescribing Information.